Developing mRNA for Therapy (Nobel Prize Lecture in Medicine)
Katalin KarikóNobel LaureateKarolinska Institutet
Nobel Laureate in Physiology or Medicine
42:16·2023·undergraduate level·Public Colloquium
Details the biochemical discovery that pseudouridine nucleoside modification suppresses innate Toll-like receptor inflammation while boosting mRNA translation.
Katalin Karikó: Developing mRNA for therapy.
The Nobel Prize in Physiology or Medicine 2023 was awarded jointly to Katalin Karikó and Drew Weissman "for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19"
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