RNA-Guided Genome Engineering with CRISPR-Cas9
Nobel Laureate in Chemistry & Li Ka Shing Chancellor's Chair
48:26·2017·undergraduate level·Research Seminar
Explains bacterial adaptive immunity and the structural mechanism by which guide RNA directs Cas9 endonuclease cleavage of double-stranded DNA.
Jennifer Doudna (University of California, Berkeley) explains the basics of CRISPR immunity, Cas9 mechanics, and anti-CRISPRs. [2017 CRISPR Workshop]
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