Skip to content
lectern.tv

RNA-Guided Genome Engineering with CRISPR-Cas9

Nobel Laureate in Chemistry & Li Ka Shing Chancellor's Chair

48:26·2017·undergraduate level·Research Seminar
Path step 2: Unpacks RNA-guided Cas9 endonuclease targeting for programmable genome editing.

Explains bacterial adaptive immunity and the structural mechanism by which guide RNA directs Cas9 endonuclease cleavage of double-stranded DNA.

Jennifer Doudna (University of California, Berkeley) explains the basics of CRISPR immunity, Cas9 mechanics, and anti-CRISPRs. [2017 CRISPR Workshop]

Comments

Add a comment...Sign in